Recombinant CD27 antibody (full length)

Catalog No. ABIN7877856

The Rabbit Monoclonal anti-CD27 antibody is suitable to detect CD27 in samples from Human. It has been validated for IHC (p).

Quick Overview for Recombinant CD27 antibody (full length) (ABIN7877856)

Target: CD27 (CD27 Molecule (CD27))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD27 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: LPFS2-8316R

Product Details anti-CD27 Antibody

Binding Specificity: full length

Purpose: CD27 Antibody (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant human full-length protein was used as the immunogen for the CD27 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the CD27 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the CD27 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CD27

Target: CD27 (CD27 Molecule (CD27))

Alternative Name: CD27

Background: Recognizes a protein of a disulfide-linked 120 kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFkB and SAPK/JNK and induces apoptosis.

UniProt: P26842

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints