Recombinant Cytokeratin 8/18 antibody (full length)

Catalog No. ABIN7878110

This Rabbit Monoclonal antibody specifically detects Cytokeratin 8/18 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant Cytokeratin 8/18 antibody (full length) (ABIN7878110)

Target: Cytokeratin 8/18

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Cytokeratin 8/18 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: KRT8-18-2297R

Product Details anti-Cytokeratin 8/18 Antibody

Binding Specificity: full length

Purpose: Recombinant Cytokeratin 8/18 Antibody (azide and preservative free)

Purification: Protein A affinity chromatography

Immunogen: Recombinant full-length human KRT8/18 protein was used as the immunogen for the recombinant Cytokeratin 8/18 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the recombinant Cytokeratin 8/18 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant Cytokeratin 8/18 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Cytokeratin 8/18

Target: Cytokeratin 8/18

Background: Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells, there is very little keratin 18 in the normal epidermis so only Paget cells are stained. Immunohistochemical staining with this MAb is indistinguishable from that obtained with monoclonal antibody 5D3.

UniProt: P05787