Recombinant Desmocollin 2+3 (full length) antibody
The Rabbit Monoclonal anti-Desmocollin 2+3 antibody (Clone DSC2-9165R) (ABIN7878136) specifically detects Desmocollin 2+3 in IHC (p).
The antibody is reactive with Human samples.
Catalog No. ABIN7878136
$640.46
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 2 to 4 Business Days
Quick Overview for Recombinant Desmocollin 2+3 (full length) antibody (ABIN7878136)
Target
Desmocollin 2+3
Antibody Type
Recombinant Antibody
Reactivity
Human
Host
Rabbit
Clonality
Monoclonal
Conjugate
Un-conjugated
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Grade
Carrier-free
Clone
DSC2-9165R
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Binding Specificity
- full length
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Purpose
- Recombinant Desmocollin-2/3 Antibody (azide and preservative free)
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Purification
- Protein A/G affinity
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Immunogen
- Recombinant full-length human DSC2 protein was used as the immunogen for the recombinant Desmocollin-2/3 antibody.
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Isotype
- IgG
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anti-Desmocollin 2+3 (Extracellular) antibody
Carrier-free Reactivity: Human, Mouse, Rat IF, WB, FACS, IHC (p) Host: Mouse Monoclonal 7G6 unconjugated
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Application Notes
- Optimal dilution of the recombinant Desmocollin-2/3 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Preservative
- Azide free
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Storage
- -20 °C
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Storage Comment
- Aliquot the recombinant Desmocollin-2/3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Desmocollin 2+3
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Alternative Name
- Desmocollin-2/3
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Background
- Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. The desmosome is subdivided into two regions. The plaque region lies adjacent to the plasma, and is believed to contain molecules that attach the intermediate filament cytoskeleton to the desmosome. The core region is composed of transmembrane glycoproteins that are thought to mediate cell-cell adhesion. Desmogleins and desmocollins are the main desmosomal transmembrane proteins. These desmosomal glycoproteins belong to the members of the cadherin family of adhesion molecules. Three different isoforms of both desmogleins and desmocollins have been identified, named as desmoglein 1-3 and desmocollins. Desmosomal cadherins showed differentiation-specific expression in the human epidermis, although the functional significance of this differential expression is not fully understood. Desmocollin-1 can be found in the upper layers. The expression of desmocollin-2 varies in the basal and suprabasal layers. And desmocollin-3 is expressed more evenly throughout the suprabasal layers.
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UniProt
- Q02487
Target
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