Recombinant MLANA antibody (N-Term)

Catalog No. ABIN7879614

The Rabbit Monoclonal anti-MLANA antibody is suitable to detect MLANA in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for Recombinant MLANA antibody (N-Term) (ABIN7879614)

Target: MLANA (Melan A (MLANA))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MLANA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: MLANA-4385R

Product Details anti-MLANA Antibody

Binding Specificity: N-Term

Purpose: Recombinant MART-1 Antibody / Melan-A (azide and preservative free)

Purification: Protein A affinity chromatography

Immunogen: A recombinant fragment corresponding to the N-terminus of human Melan A was used as the immunogen for the recombinant MART-1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the recombinant MART-1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant MART-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for MLANA

Target: MLANA (Melan A (MLANA))

Alternative Name: MART-1

Background: This antibody recognizes a protein doublet of 20-22 kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.

UniProt: Q16655