Recombinant TIMP2 antibody (N-Term)

Catalog No. ABIN7879623

The Mouse Monoclonal anti-TIMP2 antibody is suitable to detect TIMP2 in samples from Human, Rat and Mouse. It has been validated for IHC (p).

Quick Overview for Recombinant TIMP2 antibody (N-Term) (ABIN7879623)

Target: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Antibody Type: Recombinant Antibody

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This TIMP2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RTIMP2-2335

Product Details anti-TIMP2 Antibody

Binding Specificity: N-Term

Purpose: Recombinant TIMP2 Antibody

Sequence: DSGNDIYGNP I

Purification: Protein G affinity chromatography

Immunogen: Amino acids DSGNDIYGNPI (N-terminal region) were used as the immunogen for the recombinant TIMP2 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the recombinant TIMP2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant TIMP2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for TIMP2

Target: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Alternative Name: TIMP2

Background: It recognizes a protein of 21 kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

UniProt: P16035

Pathways: cAMP Metabolic Process