Recombinant Bifunctional Pantoate Ligase/cytidylate Kinase (PanC/cmk) (pan) antibody

Catalog No. ABIN7879671

The Mouse Monoclonal anti-Bifunctional Pantoate Ligase/cytidylate Kinase antibody is suitable to detect Bifunctional Pantoate Ligase/cytidylate Kinase in samples from Human. It has been validated for FACS, IF and IHC (p).

Quick Overview for Recombinant Bifunctional Pantoate Ligase/cytidylate Kinase (PanC/cmk) (pan) antibody (ABIN7879671)

Target: Bifunctional Pantoate Ligase/cytidylate Kinase (PanC/cmk)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: Cocktail rPCK-6750

Product Details

Binding Specificity: pan

Purpose: Recombinant Pan-CK Antibody Cocktail

Purification: Protein A/G affinity

Immunogen: Crude cytokeratin extract prepared from RT-4 and MCF-7 cells was used as the immunogen for the recombinant Pan-CK antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the recombinant Pan-CK antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the recombinant Pan-CK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details

Target: Bifunctional Pantoate Ligase/cytidylate Kinase (PanC/cmk)

Alternative Name: CK

Background: Anti-cytokeratin clone rPCK/6750 demonstrates a broad spectrum of cytokeratin reactivity. In normal tissues, rPCK/6750 is reactive with most epithelial types, including bile ducts and hepatocytes in liver, bladder epithelium, breast ducts, bronchial epithelium, endometrium, intestinal epithelium of stomach, duodenum, ileum, colon, rectum, pancreas, ovarian epithelium, pancreatic acini, pituitary acini, pneumocytes, prostate, thyroid, skin (positive on the basal layer and negative on the superficial layers of squamous epithelium), and apocrine and sweat glands. In tumors, rPCK/6750 is reactive with most carcinomas, including breast, transitional cell (TCC), renal cell (RCC), lung adenocarcinoma, lung small cell, lung squamous cell, endometrial, prostate, ovarian, hepatocellular (HCC), colorectal CA, stomach and thyroid. It is negative in certain normal tissues, including brain, lymphocytes and all cells of hematolymphoid origin, muscle, brain, nerves, endothelium and in certain tumors including most melanomas, sarcomas, lymphomas, primitive neuroectodermal tumors (PNET)/Ewings and gastrointestinal stromal tumors (GIST). Positivity has been seen on some dendritic cells in lymph nodes, some endothelia, and some muscle cells.