Recombinant ACAT1 antibody

Catalog No. ABIN7879856

This Rabbit Monoclonal antibody specifically detects ACAT1 in WB and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Recombinant ACAT1 antibody (ABIN7879856)

Target: ACAT1 (Acetyl-CoA Acetyltransferase 1 (ACAT1))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ACAT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: 29A55

Product Details anti-ACAT1 Antibody

Purpose: ACAT1 Antibody / Acetyl-CoA acetyltransferase

Purification: Affinity chromatography

Immunogen: A synthetic peptide specific to human Acetyl-CoA acetyltransferase protein was used as the immunogen for the ACAT1 Antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ACAT1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the ACAT1 antibody at -20oC.

Target Details for ACAT1

Target: ACAT1 (Acetyl-CoA Acetyltransferase 1 (ACAT1))

Alternative Name: ACAT1

Background: The Acetyl-CoA acetyltransferase protein, also called ACAT1, is an enzyme that catalyzes the conversion of Acetyl-CoA to acetoacetyl-CoA. This reaction is a key step in the fatty acid beta-oxidation pathway, which is essential for the breakdown of fatty acids and the production of energy. Additionally, ACAT1 plays a critical role in ketogenesis, a process that occurs during times of fasting or low carbohydrate intake. The structure of the Acetyl-CoA acetyltransferase protein is highly conserved among different species, indicating its importance in cellular metabolism. This enzyme contains an active site where the catalytic reaction takes place, as well as binding sites for its substrate and cofactors. The precise mechanism by which Acetyl-CoA is converted to acetoacetyl-CoA by this enzyme involves a series of chemical reactions that involve the transfer of acetyl groups.

UniProt: P24752