ACP2 antibody

Catalog No. ABIN7879861

The Rabbit Polyclonal anti-ACP2 antibody (ABIN7879861) specifically detects ACP2 in WB. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for ACP2 antibody (ABIN7879861)

Target: ACP2 (Acid Phosphatase 2, Lysosomal (ACP2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ACP2 Antibody

Purpose: ACP2 Antibody / Lysosomal Acid Phosphatase

Sequence: RSLRFVTLLY RHGDRSPVKT YPKDPYQE

Purification: Antigen affinity purified

Immunogen: Amino acids RSLRFVTLLYRHGDRSPVKTYPKDPYQE were used as the immunogen for the ACP2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ACP2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ACP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ACP2

Target: ACP2 (Acid Phosphatase 2, Lysosomal (ACP2))

Alternative Name: ACP2

Background: Lysosomal acid phosphatase is an enzyme that in humans is encoded by the ACP2 gene. The protein encoded by this gene belongs to the histidine acid phosphatase family, which hydrolyze orthophosphoric monoesters to alcohol and phosphate. This protein is localized to the lysosomal membrane, and is chemically and genetically distinct from the red cell acid phosphatase. Mice lacking this gene showed multiple defects, including bone structure alterations, lysosomal storage defects, and an increased tendency towards seizures. An enzymatically-inactive allele of this gene in mice showed severe growth retardation, hair-follicle abnormalities, and an ataxia-like phenotype. Alternatively spliced transcript variants have been found for this gene. A C-terminally extended isoform is also predicted to be produced by the use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism.

UniProt: P11117