CEA antibody

Catalog No. ABIN7880175

The Rabbit Polyclonal anti-CEA antibody is suitable to detect CEA in samples from Human. It has been validated for IHC (p).

Quick Overview for CEA antibody (ABIN7880175)

Target: CEA (Carcinoembryonic Antigen Gene Family (CEA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEA antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Product Details anti-CEA Antibody

Purpose: CEA Antibody / Carcinoembryonic Antigen (azide and preservative free)

Purification: Protein A affinity

Immunogen: Purified native human CEA protein was used as the immunogen for the CEA antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the CEA antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the CEA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CEA

Target: CEA (Carcinoembryonic Antigen Gene Family (CEA))

Alternative Name: CEA

Background: This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70 % are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

UniProt: P06731