GZMK antibody

Catalog No. ABIN7880925

The Rabbit Polyclonal anti-GZMK antibody is suitable to detect GZMK in samples from Human. It has been validated for IHC (p).

Quick Overview for GZMK antibody (ABIN7880925)

Target: GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GZMK antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GZMK Antibody

Purpose: GZMK Antibody / Granzyme K

Sequence: DIMLVKLQTA AKLNKHVKML HIR

Purification: Antigen affinity purified

Immunogen: Amino acids DIMLVKLQTAAKLNKHVKMLHIR were used as the immunogen for the GZMK antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the GZMK antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the GZMK antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for GZMK

Target: GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))

Alternative Name: GZMK

Background: Granzyme K is a protein that in humans is encoded by the GZMK gene. This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes

UniProt: P49863