L-Selectin antibody

Catalog No. ABIN7882224

This Mouse Monoclonal antibody specifically detects L-Selectin in FACS, WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for L-Selectin antibody (ABIN7882224)

Target: L-Selectin (SELL) (Selectin L (SELL))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This L-Selectin antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), ELISA

Clone: LAM1-116

Product Details anti-L-Selectin Antibody

Purpose: L-Selectin Antibody / CD62L

Purification: Protein G affinity chromatography

Immunogen: Supernatant from phorbol myristic acid activated human peripheral blood leukocytes was used as the immunogen for the L-Selectin antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the L-Selectin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the L-Selectin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for L-Selectin

Target: L-Selectin (SELL) (Selectin L (SELL))

Alternative Name: L-Selectin

Background: Selectins, also designated CD62 antigens, comprise a family of carbohydrate-binding proteins involved in mediating cellular interactions with leukocytes. L-Selectin (also designated LECAM-1 or CD62L) is expressed on the majority of B and naive T cells and on most monocytes, neutrophils and eosinophils. L-Selectin interacts with specific carbohydrates expressed by activated endothelial cells. P-Selectin (also designated GMP-140 or CD62P), expressed on activated platelets and endothelial cells, and E-Selectin (also designated ELMA-1 or CD62E), expressed on endothelial cells, exhibit overlapping ligand specificities. Both recognize sialyl-Le (x) as a ligand and bind to specific carbohydrates on neutrophils and monocytes.

UniProt: P14151