IL18RAP antibody (AA 15-120)

Catalog No. ABIN748058

The Rabbit Polyclonal anti-IL18RAP antibody has been validated for WB, ELISA, FACS and IP. It is suitable to detect IL18RAP in samples from Human and Mouse. There is 1 publication available.

Quick Overview for IL18RAP antibody (AA 15-120) (ABIN748058)

Target: IL18RAP (Interleukin 18 Receptor Accessory Protein (IL18RAP))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL18RAP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP)

Product Details anti-IL18RAP Antibody

Binding Specificity: AA 15-120

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IL-18R beta

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IP(1-2 μg)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-IL18RAP antibody (ABIN748058)

Valente, Yoshida, Izadpanah, Delafontaine, Siebenlist, Chandrasekar: "Interleukin-18 enhances IL-18R/Nox1 binding, and mediates TRAF3IP2-dependent smooth muscle cell migration. Inhibition by simvastatin." in: Cellular signalling, Vol. 25, Issue 6, pp. 1447-56, (2013) (PubMed).

Target Details for IL18RAP

Target: IL18RAP (Interleukin 18 Receptor Accessory Protein (IL18RAP))

Alternative Name: IL-18R Beta/CD218b

Background:

Synonyms: ACPL, CD218b, IL-1R7, IL18RB, CDw218b, IL-1R-7, IL-18RAcP, IL-1RAcPL, IL-18Rbeta, IL-18R-beta, Interleukin-18 receptor accessory protein, IL-18 receptor accessory protein, Accessory protein-like, CD218 antigen-like family member B, IL-1R accessory protein-like, Interleukin-1 receptor 7, Interleukin-18 receptor accessory protein-like, Interleukin-18 receptor beta, IL18RAP, IL1R7

Background: Required for the high affinity binding of interleukin 18 (IL-18) to its receptor complex (By similarity). Together with IL18R1 mediates IL-18-dependent activation of NF-kappa-B and JNK.

Gene ID: 8807

UniProt: O95256