CD207 antibody (AA 161-260) (Biotin)

Catalog No. ABIN748570

This Rabbit Polyclonal antibody specifically detects CD207 in WB, ELISA. It exhibits reactivity toward Mouse.

Quick Overview for CD207 antibody (AA 161-260) (Biotin) (ABIN748570)

Target: CD207 (CD207 Molecule, Langerin (CD207))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD207 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA

Product Details anti-CD207 Antibody (Biotin)

Binding Specificity: AA 161-260

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD207

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CD207

Target: CD207 (CD207 Molecule, Langerin (CD207))

Alternative Name: Langerin/CD207

Background:

Synonyms: CLEC4K, C-type lectin domain family 4 member K, Langerin, CD207

Background: Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs), is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.

Gene ID: 50489

UniProt: Q9UJ71