C5b-9 antibody (Biotin)

Catalog No. ABIN748915

This Rabbit Polyclonal antibody specifically detects C5b-9 in IHC (fro) and IHC (p). It exhibits reactivity toward Human, Rat and Mouse and has been mentioned in 2+ publications.

Quick Overview for C5b-9 antibody (Biotin) (ABIN748915)

Target: C5b-9 (Terminal Complement Complex C5b-9 (C5b-9))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C5b-9 antibody is conjugated to Biotin

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-C5b-9 Antibody (Biotin)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Purified Human SC5b-9 Complex

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

References for anti-C5b-9 antibody (Biotin) (ABIN748915)

Alvarez Arias, Kim, Zhou, Holderried, Wang, Dranoff, Cantor: "Disruption of CD8+ Treg activity results in expansion of T follicular helper cells and enhanced antitumor immunity." in: Cancer immunology research, Vol. 2, Issue 3, pp. 207-16, (2014) (PubMed).

Target Details for C5b-9

Target: C5b-9 (Terminal Complement Complex C5b-9 (C5b-9))

Background:

Synonyms: C9D, ARMD15, Complement component C9, C9

Background: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC.

Gene ID: 735

UniProt: P02748