Plexin A1 antibody (AA 901-1000) (Cy5)

Catalog No. ABIN749217

This anti-Plexin A1 antibody is a Rabbit Polyclonal antibody detecting Plexin A1 in IF (cc) and IF (p). Suitable for Mouse.

Quick Overview for Plexin A1 antibody (AA 901-1000) (Cy5) (ABIN749217)

Target: Plexin A1 (PLXNA1)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Plexin A1 antibody is conjugated to Cy5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Plexin A1 Antibody (Cy5)

Binding Specificity: AA 901-1000

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Plexin A1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Plexin A1

Target: Plexin A1 (PLXNA1)

Alternative Name: Plexin A1

Background:

Synonyms: NOV, NOVP, PLXN1, PLEXIN-A1, Semaphorin receptor NOV, PLXNA1

Background: Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity).

Gene ID: 5361

UniProt: Q9UIW2

Pathways: Smooth Muscle Cell Migration