IL27 Receptor alpha antibody (AA 21-120)

Catalog No. ABIN749498

The Rabbit Polyclonal anti-IL27 Receptor alpha antibody has been validated for WB, ELISA, ICC, IF (cc), IF (p), IHC (p) and IHC (fro). It is suitable to detect IL27 Receptor alpha in samples from Human and Mouse. There is 1 publication available.

Quick Overview for IL27 Receptor alpha antibody (AA 21-120) (ABIN749498)

Target: IL27 Receptor alpha (IL27RA) (Interleukin 27 Receptor, alpha (IL27RA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL27 Receptor alpha antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-IL27 Receptor alpha Antibody

Binding Specificity: AA 21-120

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IL-27RA

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-IL27 Receptor alpha antibody (ABIN749498)

Xu, Yi, Wang, Hu, Han, Xue, Zhang, Luan: "IL-27 regulates the adherence, proliferation, and migration of MSCs and enhances their regulatory effects on Th1 and Th2 subset generations." in: Immunologic research, Vol. 65, Issue 4, pp. 903-912, (2017) (PubMed).

Target Details for IL27 Receptor alpha

Target: IL27 Receptor alpha (IL27RA) (Interleukin 27 Receptor, alpha (IL27RA))

Alternative Name: Il-27ra

Background:

Synonyms: CRL1, TCCR, WSX1, IL27R, IL-27RA, zcytor1, Interleukin-27 receptor subunit alpha, IL-27 receptor subunit alpha, IL-27R subunit alpha, IL-27R-alpha, Cytokine receptor WSX-1, Cytokine receptor-like 1, Type I T-cell cytokine receptor, IL27RA, UNQ296/PRO336

Background: Receptor for IL27. Requires IL6ST/gp130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Involved in the regulation of Th1-type immune responses. Also appears to be involved in innate defense mechanisms.

Gene ID: 9466

UniProt: Q6UWB1

Pathways: Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response