STS antibody (AA 51-150) (HRP)

Catalog No. ABIN750217

This Rabbit Polyclonal antibody specifically detects STS in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for STS antibody (AA 51-150) (HRP) (ABIN750217)

Target: STS (Steroid Sulfatase (Microsomal), Isozyme S (STS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STS antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-STS Antibody (HRP)

Binding Specificity: AA 51-150

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Steroid sulfatase

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for STS

Target: STS (Steroid Sulfatase (Microsomal), Isozyme S (STS))

Alternative Name: Ssdd/Steroid Sulfatase

Background:

Synonyms: ARSC, ARSC1, Arylsulfatase C, Arylsulfatase C isozyme S, ASC, EC 3.1.6.2, ES, Estrone sulfatase, SSDD, Steroid sulfatase microsomal, Steroid sulfatase microsomal arylsulfatase C isozyme S, Steroid sulfatase, Steryl sulfatase, Steryl sulfatase precursor, Steryl sulfate sulfohydrolase, STS, STS_HUMAN, Steryl-sulfatase, ASC, Steryl-sulfate sulfohydrolase.

Background: The protein encoded by this gene catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The encoded protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in this gene are known to cause X-linked ichthyosis (XLI). [provided by RefSeq, Jul 2008].

Gene ID: 412

Pathways: Steroid Hormone Biosynthesis