ALOX12 antibody (AA 101-200)

Catalog No. ABIN750463

This Rabbit Polyclonal antibody specifically detects ALOX12 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for ALOX12 antibody (AA 101-200) (ABIN750463)

Target: ALOX12 (Arachidonate 12-Lipoxygenase (ALOX12))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALOX12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ALOX12 Antibody

Binding Specificity: AA 101-200

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human 12 Lipoxygenase

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ALOX12

Target: ALOX12 (Arachidonate 12-Lipoxygenase (ALOX12))

Alternative Name: ALOX12/12 Lipoxygenase

Background:

Synonyms: 12 Lox, 12S lipoxygenase, 12S LOX, Alox 12, Alox12, Alox12L, Alox15, Arachidonate 12 lipoxygenase 12S type, Arachidonate 12 lipoxygenase, Arachidonate 12 lipoxygenase leukocyte type, Arachidonate 12 lipoxygenase, 12S type, Arachidonate 12 lipoxygenase, leukocyte type, EC1.13.11.31, LOG 12, LOG12, Platelet type 12 lipoxygenase, Platelet type lipoxygenase 12, P-12-LOX.

Background: 12 Lipoxygenase is a non heme iron containing dioxygenase which stereospecifically incorporates molecular oxygen into cis,cis-1,4-pentadiene containing polyunsaturated fatty acids. Murine leukocyte 12 Lipoxygenase oxidizes arachidonic acid to 12(S)-HpETE and 15(S)-HpETE in a ratio of 3:1. Murine leukocyte 12 Lipoxygenase is a 75 kDa protein which is 58 % homologous to murine platelet 12 Lipoxygenase, and 70 % homologous to porcine leukocyte 12 Lipoxygenase.

Gene ID: 239

Pathways: Positive Regulation of Endopeptidase Activity