ATG4C antibody (AA 201-300) (Biotin)

Catalog No. ABIN752460

This anti-ATG4C antibody is a Rabbit Polyclonal antibody detecting ATG4C in WB, ELISA, IHC (p) and IHC (fro). Suitable for Human and Mouse.

Quick Overview for ATG4C antibody (AA 201-300) (Biotin) (ABIN752460)

Target: ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG4C antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ATG4C Antibody (Biotin)

Binding Specificity: AA 201-300

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ATG4C

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for ATG4C

Target: ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))

Alternative Name: ATG4C

Background:

Synonyms: APG4 autophagy 4 homolog C S. cerevisiae, APG4 autophagy 4 homolog C, APG4 C, APG4-C, APG4C, ATG 4C, ATG4 autophagy related 4 homolog C S. cerevisiae, Atg4C, ATG4C_HUMAN, AUT S. cerevisiae like 1, cysteine endopeptidase, AUT like 1, cysteine endopeptidase S. cerevisiae, AUT like 1, cysteine endopeptidase, AUT like 3 cysteine endopeptidase, AUT-like 3 cysteine endopeptidase, AUTL1, AUTL3, Autophagin 3, Autophagin-3, Autophagy related cysteine endopeptidase 3, Autophagy related protein 4 homolog C, Autophagy-related cysteine endopeptidase 3, Autophagy-related protein 4 homolog C, Cysteine protease ATG4C, EC 3.4.22, FLJ14867, OTTHUMP00000010715.

Background: Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.

Gene ID: 84938

Pathways: Autophagy