DEGS1 antibody (AA 21-120) (HRP)

Catalog No. ABIN753202

This Rabbit Polyclonal antibody specifically detects DEGS1 in ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for DEGS1 antibody (AA 21-120) (HRP) (ABIN753202)

Target: DEGS1 (Sphingolipid Delta(4)-Desaturase DES1 (DEGS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEGS1 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-DEGS1 Antibody (HRP)

Binding Specificity: AA 21-120

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DEGS1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DEGS1

Target: DEGS1 (Sphingolipid Delta(4)-Desaturase DES1 (DEGS1))

Alternative Name: DEGS1

Background:

Synonyms: Degenerative spermatocyte homolog 1, Degenerative spermatocyte homolog 1 lipid desaturase, Degenerative spermatocyte homolog lipid desaturase, DEGS 1, DEGS, Des 1, DES1, Dihydroceramide desaturase, FADS7, Membrane fatty acid lipid desaturase, Membrane lipid desaturase, MGC5079, MIG15v Migration inducing gene 15 protein, MLD, Sphingolipid delta 4 desaturase, Sphingolipid delta4 desaturase DES1.DEGS1_HUMAN

Background: DEGS1 is a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. It contains three His containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It has sphingolipid-delta-4-desaturase activity and converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine).

Gene ID: 653121

UniProt: O15121