CTNNBIP1 antibody (AA 3-70)

Catalog No. ABIN753748

This Rabbit Polyclonal antibody specifically detects CTNNBIP1 in WB, ELISA, IF (cc), IF (p), IHC (fro) and IHC (p). It exhibits reactivity toward Human and Mouse and has been mentioned in 2+ publications.

Quick Overview for CTNNBIP1 antibody (AA 3-70) (ABIN753748)

Target: CTNNBIP1 (Catenin, beta Interacting Protein 1 (CTNNBIP1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTNNBIP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CTNNBIP1 Antibody

Binding Specificity: AA 3-70

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CTNNBIP1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-CTNNBIP1 antibody (ABIN753748)

Qi, Chen, Cheng, Huang, Xiang, Li, Long, Zhu: "Targeting the Wnt-Regulatory Protein CTNNBIP1 by micro RNA-214 Enhances the Stemness and Self-Renewal of Cancer Stem-Like Cells in Lung Adenocarcinomas." in: Stem cells (Dayton, Ohio), (2015) (PubMed).

Huang, Caputo, Noordmans, Yazdani, Monteiro, van den Born, van Goor, Heeringa, Korstanje, Hillebrands: "Identification of novel genes associated with renal tertiary lymphoid organ formation in aging mice." in: PloS one, Vol. 9, Issue 3, pp. e91850, (2015) (PubMed).

Target Details for CTNNBIP1

Target: CTNNBIP1 (Catenin, beta Interacting Protein 1 (CTNNBIP1))

Alternative Name: CTNNBIP1

Background:

Synonyms: ICAT, Beta-catenin-interacting protein 1, Inhibitor of beta-catenin and Tcf-4, CTNNBIP1

Background: Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway.

Gene ID: 56998

UniProt: Q9NSA3