Asialoglycoprotein Receptor 1 antibody (AA 201-291) (HRP)

Catalog No. ABIN754117

This Rabbit Polyclonal antibody specifically detects Asialoglycoprotein Receptor 1 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Asialoglycoprotein Receptor 1 antibody (AA 201-291) (HRP) (ABIN754117)

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Asialoglycoprotein Receptor 1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA

Product Details anti-Asialoglycoprotein Receptor 1 Antibody (HRP)

Binding Specificity: AA 201-291

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ASGPR1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Asialoglycoprotein Receptor 1

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Alternative Name: ASGPR1

Background:

Synonyms: HL-1, ASGPR, ASGPR1, CLEC4H1, Asialoglycoprotein receptor 1, ASGP-R 1, ASGPR 1, C-type lectin domain family 4 member H1, Hepatic lectin H1, ASGR1

Background: Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.

Gene ID: 432

UniProt: P07306

Pathways: Thyroid Hormone Synthesis