PCDHB13 antibody (AA 151-250) (Biotin)

Catalog No. ABIN758488

This Rabbit Polyclonal antibody specifically detects PCDHB13 in ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for PCDHB13 antibody (AA 151-250) (Biotin) (ABIN758488)

Target: PCDHB13 (Protocadherin beta 13 (PCDHB13))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHB13 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PCDHB13 Antibody (Biotin)

Binding Specificity: AA 151-250

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PCDHB13

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for PCDHB13

Target: PCDHB13 (Protocadherin beta 13 (PCDHB13))

Alternative Name: PCDHB13

Background:

Synonyms: Protocadherin beta 13, PCDH BETA13, PCDHB13, PCDBD_HUMAN

Background: Cadherins are calcium-dependent cell-cell adhesion molecules, and protocadherins constitute a subfamily of nonclassic cadherins. Protocadherin beta 13 is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

Gene ID: 56123