DAB2IP antibody (PE-Cy7)

Catalog No. ABIN760959

This anti-DAB2IP antibody is a Rabbit Polyclonal antibody detecting DAB2IP in WB. Suitable for Human, Mouse, Rat, Guinea Pig, Cow, Dog and Pig.

Quick Overview for DAB2IP antibody (PE-Cy7) (ABIN760959)

Target: DAB2IP (DAB2 Interacting Protein (DAB2IP))

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAB2IP antibody is conjugated to PE-Cy7

Application: Western Blotting (WB)

Product Details anti-DAB2IP Antibody (PE-Cy7)

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DAB2IP

Isotype: IgG

Application Details

Application Notes: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DAB2IP

Target: DAB2IP (DAB2 Interacting Protein (DAB2IP))

Alternative Name: DAB2IP

Background:

Synonyms: AF9Q34, AIP1, ASK interacting protein, DAB2P_HUMAN, ASK interacting protein 1, ASK1 interacting protein 1, DAB2 interacting protein, DAB2 interaction protein, DAB2P, DIP1/2, Disabled homolog 2 interacting protein, DOC 2/DAB2 interactive protein, FLJ39072, KIAA1743, nGAP like protein.

Background: DAB2IP is a Ras GTPase-activating protein (GAP) that acts as a tumor suppressor gene and is inactivated by methylation in prostate and breast cancers. It also interacts with MAP3K5 to disrupt the association of MAP3K5 with the inhibitory 14-3-3 complex.

Molecular Weight: 132kDa

Gene ID: 153090

Pathways: EGFR Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Tube Formation