RBBP5 antibody (AA 131-230)

Catalog No. ABIN761201

The Rabbit Polyclonal anti-RBBP5 antibody is suitable to detect RBBP5 in samples from Rat. It has been validated for ELISA, IF (cc), IF (p), IHC (p) and IHC (fro).

Quick Overview for RBBP5 antibody (AA 131-230) (ABIN761201)

Target: RBBP5 (Retinoblastoma Binding Protein 5 (RBBP5))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBBP5 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-RBBP5 Antibody

Binding Specificity: AA 131-230

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RBBP5

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for RBBP5

Target: RBBP5 (Retinoblastoma Binding Protein 5 (RBBP5))

Alternative Name: Rbbp5

Background:

Synonyms: RBQ3, SWD1, Retinoblastoma-binding protein 5, RBBP-5, Retinoblastoma-binding protein RBQ-3, RBBP5

Background: In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid (By similarity). As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.

Gene ID: 5929

UniProt: Q15291