POU6F2 antibody (AA 531-640) (HRP)

Catalog No. ABIN762200

The Rabbit Polyclonal anti-POU6F2 antibody has been validated for WB, ELISA, IHC (fro) and IHC (p). It is suitable to detect POU6F2 in samples from Human.

Quick Overview for POU6F2 antibody (AA 531-640) (HRP) (ABIN762200)

Target: POU6F2 (POU Class 6 Homeobox 2 (POU6F2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POU6F2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-POU6F2 Antibody (HRP)

Binding Specificity: AA 531-640

Predicted Reactivity: Human,Mouse,Rat,Dog,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human POU6F2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for POU6F2

Target: POU6F2 (POU Class 6 Homeobox 2 (POU6F2))

Alternative Name: POU6F2

Background:

Synonyms: POU class 6 homeobox 2, POU domain class 6 transcription factor 2, Retina derived POU domain factor 1, RPF 1, RPF1, Wilms tumor suppressor locus, WT 5, WT5, WTSL, PO6F2_HUMAN.

Background: This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene ID: 11281