RASSF8 antibody (AA 101-200)

Catalog No. ABIN762266

The Rabbit Polyclonal anti-RASSF8 antibody is suitable to detect RASSF8 in samples from Human. It has been validated for WB, ELISA, IF (cc), IF (p), IHC (p) and IHC (fro).

Quick Overview for RASSF8 antibody (AA 101-200) (ABIN762266)

Target: RASSF8 (Ras Association (RalGDS/AF-6) Domain Family (N-terminal) Member 8 (RASSF8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASSF8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-RASSF8 Antibody

Binding Specificity: AA 101-200

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RASSF8

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for RASSF8

Target: RASSF8 (Ras Association (RalGDS/AF-6) Domain Family (N-terminal) Member 8 (RASSF8))

Alternative Name: Rassf8

Background:

Synonyms: HOJ1, C12orf2, Ras association domain-containing protein 8, Carcinoma-associated protein HOJ-1, RASSF8

Background: This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12,22)(p11.2,q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene ID: 11228

UniProt: Q8NHQ8

Pathways: Chromatin Binding