TMEFF1 antibody (AA 65-160)

Catalog No. ABIN762686

There is 1 publication for this product available. The Rabbit Polyclonal anti-TMEFF1 antibody is suitable to detect TMEFF1 in samples from Rat. It has been validated for ELISA, IF (p), IF (cc), IHC (fro) and IHC (p).

Quick Overview for TMEFF1 antibody (AA 65-160) (ABIN762686)

Target: TMEFF1 (Transmembrane Protein with EGF-Like and Two Follistatin-Like Domains 1 (TMEFF1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEFF1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TMEFF1 Antibody

Binding Specificity: AA 65-160

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Tomoregulin-1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-TMEFF1 antibody (ABIN762686)

Bao, Lu, Liu, Dong, Lu, Qin, Zhang: "Tomoregulin-1 prevents cardiac hypertrophy after pressure overload in mice by inhibiting TAK1-JNK pathways." in: Disease models & mechanisms, Vol. 8, Issue 8, pp. 795-804, (2015) (PubMed).

Target Details for TMEFF1

Target: TMEFF1 (Transmembrane Protein with EGF-Like and Two Follistatin-Like Domains 1 (TMEFF1))

Alternative Name: Tomoregulin-1

Background:

Synonyms: TR-1, H7365, C9orf2, CT120.1, Tomoregulin-1, Transmembrane protein with EGF-like and one follistatin-like domain, TMEFF1

Background: May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers.

Gene ID: 8577

UniProt: Q8IYR6