WTX antibody (AA 281-380) (HRP)

Catalog No. ABIN762815

The Rabbit Polyclonal anti-WTX antibody has been validated for ELISA, WB, IHC (p) and IHC (fro). It is suitable to detect WTX in samples from Human.

Quick Overview for WTX antibody (AA 281-380) (HRP) (ABIN762815)

Target: WTX (AMER1) (APC Membrane Recruitment Protein 1 (AMER1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WTX antibody is conjugated to HRP

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-WTX Antibody (HRP)

Binding Specificity: AA 281-380

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FAM123B/AMER1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for WTX

Target: WTX (AMER1) (APC Membrane Recruitment Protein 1 (AMER1))

Alternative Name: FAM123B

Background:

Synonyms: AMER1, FAM 123B, Family with sequence similarity 123B, FLJ39827, OSCS, Protein FAM123B, RP11 403E24.2, Wilms tumor gene on the X chromosome protein, Wilms tumor on the X, WTX, AMER1_HUMAN.

Background: The protein encoded by this gene upregulates trancriptional activation by the Wilms tumor protein and interacts with many other proteins, including CTNNB1, APC, AXIN1, and AXIN2. Defects in this gene are a cause of osteopathia striata with cranial sclerosis (OSCS).

Gene ID: 139285