Ataxin 1 antibody (AA 686-699)

Catalog No. ABIN768538

This Goat Polyclonal antibody specifically detects Ataxin 1 in ELISA. It exhibits reactivity toward Human.

Quick Overview for Ataxin 1 antibody (AA 686-699) (ABIN768538)

Target: Ataxin 1 (ATXN1)

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This Ataxin 1 antibody is un-conjugated

Application: ELISA

Grade: Recent

Product Details anti-Ataxin 1 Antibody

Binding Specificity: AA 686-699

Purpose: ATXN1 (aa686-699)

Sequence: TLKNLKNGSV KKGQ

Specificity: Reported variants represent identical protein: NP_001121636.1, NP_000323.2

Cross-Reactivity: Cow, Human, Mouse, Pig, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-TLKNLKNGSVKKGQ, from the internal region of the protein sequence according to NP_000323.2.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Preliminary experiments gave bands at approx 75 kDa and 26 kDa in Mouse Fetal Brain lysates after 0.5 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calcul

Peptide ELISA: antibody detection limit dilution 1:32000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for Ataxin 1

Target: Ataxin 1 (ATXN1)

Alternative Name: ATXN1

Background: ATXN1, ataxin 1, ATX1, D6S504E, SCA1, OTTHUMP00000016065, ataxin-1, spinocerebellar ataxia type 1 protein

Molecular Weight: 75kDa and 26kDa

Gene ID: 6310, 20238, 25049

NCBI Accession: NP_000323

Pathways: Synaptic Membrane