TXNDC5 antibody (AA 281-295)

Catalog No. ABIN768549

This anti-TXNDC5 antibody is a Goat Polyclonal antibody detecting TXNDC5 in WB, ELISA and IHC. Suitable for Human and Mouse.

Quick Overview for TXNDC5 antibody (AA 281-295) (ABIN768549)

Target: TXNDC5 (Thioredoxin Domain Containing 5 (Endoplasmic Reticulum) (TXNDC5))

Reactivity: Human, Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This TXNDC5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Grade: Verified

Product Details anti-TXNDC5 Antibody

Binding Specificity: AA 281-295

Purpose: TXNDC5 (aa281-295)

Sequence: RDLESLREYV ESQLQ

Specificity: This antibody is expected to recognize both reported isoforms (NP_110437.2, NP_001139021.1).

Cross-Reactivity: Cow, Human, Mouse

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-RDLESLREYVESQLQ, from the internal region of the protein sequence according to NP_110437.2, NP_001139021.1.

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry: Paraffin embedded Human Small Intestine. Recommended concentration: 3.75 μg/mL.

Western Blot: Approx 50 kDa plus faint 35 kDa bands observed in Human Lymph Nodes lysates and 48 kDa in Mouse Lymph Node and in Mouse Intestine lysates (calculated MW of 47.6 kDa according to Human NP_110437.2, 46.4 kDa to Mouse NP_663342.3) and of 36.2 kDa ac

Peptide ELISA: antibody detection limit dilution 1:16000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for TXNDC5

Target: TXNDC5 (Thioredoxin Domain Containing 5 (Endoplasmic Reticulum) (TXNDC5))

Alternative Name: TXNDC5

Background: TXNDC5, thioredoxin domain containing 5 (endoplasmic reticulum), ERP46, EndoPDI, Hcc-2, MGC3178, PDIA15, UNQ364, ER protein 46, endoplasmic reticulum protein ERp46, endoplasmic reticulum resident protein 46, endothelial protein disulphide isomerase, prote

Molecular Weight: 47.6kDa according to NP_110437.2

Gene ID: 81567, 105245

NCBI Accession: NP_110437, NP_001139021

Pathways: Cell RedoxHomeostasis