NFASC antibody (AA 877-890)

Catalog No. ABIN768573

This anti-NFASC antibody is a Goat Polyclonal antibody detecting NFASC in WB and ELISA. Suitable for Human.

Quick Overview for NFASC antibody (AA 877-890) (ABIN768573)

Target: NFASC (Neurofascin (NFASC))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This NFASC antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Verified

Product Details anti-NFASC Antibody

Binding Specificity: AA 877-890

Purpose: Neurofascin (aa877-890)

Sequence: NFSPNQTKFT VQRT

Specificity: This antibody is expected to recognize reported isoforms 1, 2, 3 and 4 (NP_001005388.2,NP_001153803.1, NP_001153804.1and NP_055905.2 resp) .

Cross-Reactivity: Cow, Dog, Human, Mouse, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-NFSPNQTKFTVQRT, from the internal region of the protein sequence according to NP_001005388.2, NP_001153803.1, NP_001153804.1, NP_055905.2,.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 170 kDa band observed in Human Lung lysates (calculated MW of 138 kDa according to NP_001005388.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Kirschbaum et al, J Biol Chem. 2

Peptide ELISA: antibody detection limit dilution 1:16000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for NFASC

Target: NFASC (Neurofascin (NFASC))

Alternative Name: NFASC

Background: NFASC, neurofascin, DKFZp686P2250, FLJ46866, KIAA0756, NF, NRCAML, OTTHUMP00000065316, OTTHUMP00000065319, OTTHUMP00000065322, OTTHUMP00000065323, OTTHUMP00000065324, neurofascin homolog

Molecular Weight: 138kDa according to NP_001005388.2

Gene ID: 23114, 269116, 116690

NCBI Accession: NP_001005388, NP_001153803, NP_001153804, NP_055905

Pathways: Cell-Cell Junction Organization