TSH receptor antibody (AA 101-115)

Catalog No. ABIN768652

This Goat Polyclonal antibody specifically detects TSH receptor in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for TSH receptor antibody (AA 101-115) (ABIN768652)

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This TSH receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Verified

Product Details anti-TSH receptor Antibody

Binding Specificity: AA 101-115

Purpose: TSHR (aa101-115)

Sequence: SKVTHIEIRN TRNLT

Specificity: This antibody is expected to recognize reported isoform 1 (NP_000360.2) and isoform 2 (NP_001018046.1). The immunizing peptide sequence corresponds to a part of the extracellular domain.

Cross-Reactivity: Cow, Human

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-SKVTHIEIRNTRNLT, from the internal region of the protein sequence according to NP_000360.2, NP_001018046.1.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 28 kDa band observed in Human Thyroid Gland lysates (calculated MW of 28.4 kDa according to NP_001018046.1). Recommended concentration: 0.5-2 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:16000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for TSH receptor

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Alternative Name: TSHR

Background: TSHR, thyroid stimulating hormone receptor, CHNG1, LGR3, MGC75129, hTSHR-I, TSH-R, seven transmembrane helix receptor, thyroid-stimulating hormone receptor, thyrotropin receptor, thyrotropin receptor-I, hTSHR-I

Molecular Weight: 28.4kDa according to NP_001018046.1

Gene ID: 7253

NCBI Accession: NP_000360, NP_001018046

Pathways: Thyroid Hormone Synthesis