MED1 antibody

Catalog No. ABIN781182

The Mouse Monoclonal anti-MED1 antibody is suitable to detect MED1 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for MED1 antibody (ABIN781182)

Target: MED1 (Mediator Complex Subunit 1 (MED1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MED1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MED1 Antibody

Specificity: Nucleus

Purification: Protein G-Sepharose affinity purified

Immunogen: Recombinant fragment of Human MED1 (C-terminus).

Isotype: IgG

Application Details

Application Notes: Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 50µg/50µl

Buffer: 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for MED1

Target: MED1 (Mediator Complex Subunit 1 (MED1))

Alternative Name: MED1

Background: MED1 work with coactivators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. It also regulates p53 dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize.

Molecular Weight: 45kDa

NCBI Accession: NM_004774

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha