HDAC3 antibody
Quick Overview for HDAC3 antibody (ABIN781200)
Target
See all HDAC3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- Nucleus
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Purification
- Protein G-Sepharose affinity purified
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Immunogen
- Recombinant full length of human HDAC3.
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Isotype
- IgG
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Application Notes
- Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 50µg/50µl
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Buffer
- 0.02% Sodium Azide, 50% glycerol, 1% BSA, PBS, pH7.4.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- HDAC3 (Histone Deacetylase 3 (HDAC3))
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Alternative Name
- HDAC3
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Background
- Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone acetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
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Molecular Weight
- 80kDa
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NCBI Accession
- NP_003874
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Pathways
- Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Target
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