FIP200 antibody

Catalog No. ABIN781248

The Mouse Monoclonal anti-FIP200 antibody has been validated for WB and ELISA. It is suitable to detect FIP200 in samples from Human.

Quick Overview for FIP200 antibody (ABIN781248)

Target: FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FIP200 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FIP200 Antibody

Specificity: Nucleus

Purification: Protein G-Sepharose affinity purified

Immunogen: Recombinant fragment of Human RB1CC1 (N-terminus).

Isotype: IgG

Application Details

Application Notes: Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 50µg/50µl

Buffer: 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for FIP200

Target: FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))

Alternative Name: RB1CC1

Background: The RB1CC1 protein is a key regulator of the tumor suppressor gene RB1.It is localized in the nucleus and has been proposed to be a transcriptionfactor because of its nuclear localization signal, leucine zipper motif, andcoiled-coil structure. 20% of primary breast cancers contain mutations inRB1CC1 which shows characteristics of a classic tumor suppressor gene.

Molecular Weight: 40kDa

NCBI Accession: NM_014781

Pathways: Regulation of Cell Size, Autophagy