Phenytoin antibody
Quick Overview for Phenytoin antibody (ABIN781513)
Target
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Purification
- Protein A Chromatography
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.1 mg/mL (OD280nm)
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Buffer
- PBS, pH 7.4 without preservatives
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Preservative
- Without preservative
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- Phenytoin
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Target Type
- Chemical
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Background
- Phenytoin is an anticonvulsant drug which can be useful in the treatment of epilepsy. Phenytoin blocks voltage-sensitive sodium channels in neurons. This action leads to a delay in neuronal electrical recovery. Phenytoin's inhibitory effect is dependent on the voltage and frequency of neural cell firing by selectively blocking the neurons that are firing at high frequency. Phenytoin prevents the electrical spread of a focus of irritable tissue from entering normal tissue. Phenytoin reduces the maximal activity of brain stem centers responsible for the tonic phase of tonic clonic (grand mal) seizures. Chemical formula: 5,5-diphenyl-2,4-imidazolidinedione.Synonyms: 4-dione, 5, 5-diphenylimidazolidine-2, Dilantin, Diphenylhydantoin, Epanutin, Phenytek
Target
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