CD24 antibody

Catalog No. ABIN781712

The Mouse Monoclonal anti-CD24 antibody is suitable to detect CD24 in samples from Human. It has been validated for FACS and IHC (fro).

Quick Overview for CD24 antibody (ABIN781712)

Target: CD24 (CD24 Molecule (CD24))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD24 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 32D12

Product Details anti-CD24 Antibody

Specificity: This antibody detects CD24.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Reconstitute by adding 0.5 mL distilled water.

Buffer: Stock solution contains 0.2 mg/mL IgG, phosphate buffered saline pH 7.2 (PBS), 5 mg/mL bovine serum albumin (BSA), and 0.09 % sodium azide as a preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.

Target Details for CD24

Target: CD24 (CD24 Molecule (CD24))

Alternative Name: CD24

Background: CD24 antigen is expressed throughout Bcell development and is downregulated as bone marrow progenitors mature. CD24 expression is lost when human B-cells become plasma cells. The cellular function for human CD24 is unknown so far. Diagnostically, it can serve as a marker for staging B-cell development, and it is expressed at high levels in small cell lung carcinoma. CD24 is a member of a family that also includes Heat Stable Antigen HSA and CD52. It is a glycosylphosphatidylinositol (GPI) anchored glycoprotein.Synonyms: HSA, Signal transducer CD24, Small cell lung carcinoma cluster 4 antigen, X62 heat stable antigen

Gene ID: 100133941

NCBI Accession: NP_037362

UniProt: P25063

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation