CD37 antibody

Catalog No. ABIN781713

The Mouse Monoclonal anti-CD37 antibody (Clone HH1) (ABIN781713) specifically detects CD37 in FACS and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for CD37 antibody (ABIN781713)

Target: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD37 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: HH1

Product Details anti-CD37 Antibody

Specificity: This Monoclonal HH1 antibody recognizes the CD37 antigen. Antigen Distribution Isolated cells: The antibody strongly stains approximately 2-10 % of human peripheral blood mononuclear cells in flow cytometry. CD37 is present at low density on resting and activated T cells, neutrophils, monocytes and some myelomonocytic leukemia cells. Tissue Sections: The antibody shows a B cell restricted staining pattern.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS, pH 7.2, 0.09 % Sodium Azide, 5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.

Target Details for CD37

Target: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Alternative Name: CD37

Background: CD37 is strongly expressed on normal and neoplastic mature B lymphocytes. In B-cell ontogeny, the antigen appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. Due to its strong expression, CD37 is a valuable and stable marker for peripheral mature B cells and malignancies thereof. CD37 is extensively glycosylated and typically precipitates as a broad band ranging from 42 to 52kD.Synonyms: Leukocyte antigen CD37, TSPAN26, Tetraspanin-26

Gene ID: 951

NCBI Accession: NP_001765

UniProt: P11049

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response