Transferrin Receptor antibody

Catalog No. ABIN781719

This anti-Transferrin Receptor antibody is a Mouse Monoclonal antibody detecting Transferrin Receptor in FACS and IHC (fro). Suitable for Human.

Quick Overview for Transferrin Receptor antibody (ABIN781719)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Transferrin Receptor antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: SOM4D10

Product Details anti-Transferrin Receptor Antibody

Specificity: This antibody recognizes the human CD71 antigen, the transferrin receptor.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Affinity chromatography

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Reconstitute by adding 0.5 mL distilled water.

Buffer: Stock solution contains 0.4 mg/mL IgG, phosphate buffered saline pH 7.2 (PBS), 5 mg/mL bovine serum albumin (BSA), and 0.09 % sodium azide as a preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.

Target Details for Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Alternative Name: CD71 / TFRC

Background: CD71 is a proliferation-associated homodimeric membrane glycoprotein consisting of two disulfide-bonded 95kD chains. CD71 is a type II membrane protein with short aminoterminal cytoplasmic domain which mediates internalization and recycling, a single transmembrane region, and a large extracellular transferrin-binding domain. CD71 contains N-linked and O-linked glycans, as well as palmitic acid covalently attached to cysteine residues close to the cytoplasmic face of the membrane.Synonyms: TfR1, Transferrin receptor protein 1, p90

Gene ID: 7037

NCBI Accession: NP_001121620

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis