CRP
Reactivity: Rat
WB, IHC, ICC, IP
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Concentration
1.0 mg/mL
Buffer
Phosphate buffered saline pH 7.2 (PBS), and 0.09 % sodium azide as a preservative. No stabilizing protein has been added.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Target
CRP
(C-Reactive Protein (CRP))
Background
Monoclonal antibody PC1 recognizes porcine C-reactive protein (CRP). CRP belongs to a highly conserved phylogenetically ancient family called pentraxins, which have five identical non-covalently linked subunits. Native CRP in its pentameric form has a molecular weight of approximately 115 kDa. As in humans, CRP is an acute-phase protein in pigs. It has been suspected to be directly involved in the pathogenesis of ischemic diseases through the activation of the complement system. CRP levels have been measured in porcine serum. Median levels in specific pathogen-free animals were 5 μg/mL and increased 40- to 70-fold due to inflammation or infection with Mycoplasma hyopneumoniae.Synonyms: C Reactive Protein, PTX1, Pentraxin-related