CD163 antibody
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- Target See all CD163 Antibodies
- CD163
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD163 antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- This antibody recognizes CD163, an approximately 130 kDa high affinity scavenger receptor expressed mainly on monocytes and macrophages, which binds hemoglobin-haptoglobin complex.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human
- Purification
- Protein-A affinity chromatography
- Purity
- > 95 % pure (by SDS-PAGE)
- Immunogen
- Hairy cell leukemia cells
- Clone
- GHI-61
- Isotype
- IgG1
- Top Product
- Discover our top product CD163 Primary Antibody
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anti-CD163 (CD163) (AA 1001-1121) antibody
CD163 Reactivity: Human, Mouse, Rat, Pig, Dog WB, FACS, ELISA, IHC (p), IHC (fro), ICC, IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
anti-CD163 (CD163) (AA 1001-1121) antibody (FITC)CD163 Reactivity: Human, Mouse, Rat, Pig, Dog WB, FACS, IF (cc), IF (p) Host: Rabbit Polyclonal FITC
anti-CD163 (CD163) (AA 42-259) antibodyCD163 Reactivity: Human WB, FACS, IHC, ELISA Host: Mouse Monoclonal 7G5E2 unconjugated
anti-CD163 (CD163) (AA 43-196) antibodyCD163 Reactivity: Human IHC, ELISA, ISt, Coat, StM Host: Mouse Monoclonal M130-2162 unconjugated
anti-CD163 (CD163) (AA 43-196) antibodyCD163 Reactivity: Human WB, IHC, ISt, StM Host: Mouse Monoclonal M130-1210 unconjugated
anti-CD163 (CD163) antibodyCD163 Reactivity: Human WB, FACS, IP, IHC (fro) Host: Mouse Monoclonal GHI-61 unconjugated
anti-CD163 (CD163) (AA 697-972) antibodyCD163 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-CD163 (CD163) (AA 1092-1109), (C-Term) antibodyCD163 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-CD163 (CD163) (AA 47-201) antibodyCD163 Reactivity: Human, Mouse, Rat WB, FACS, IHC, ELISA, ICC Host: Rabbit Polyclonal unconjugated
anti-CD163 (CD163) (AA 693-939) antibodyCD163 Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH ~7.4, 15 mM Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- Target
- CD163
- Alternative Name
- CD163 (CD163 Products)
- Background
- CD163, also known as M130, is a member of the scavenger receptor family, accounting for the clearance of hemoglobin-haptoglobin complexes during limited hemolysis, which protects the body, in particular the kidneys, against heme-mediated oxidative damages. It does not have measurable affinity for noncomplexed hemoglobin or haptoglobin. Immunomodulatory role of CD163 has been postulated. CD163 is expressed by cells of the monocyte-macrophage lineage and its extracellular part also circulates in plasma as a soluble protein, especially during sepsis and other conditions affecting macrophage activity, when its level may raise manyfold.Synonyms: Hemoglobin scavenger receptor, M130, Macrophage marker, Scavenger receptor cysteine-rich type 1 protein M130
- Gene ID
- 9332
- NCBI Accession
- NP_004235
- UniProt
- Q86VB7
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