NEK2 antibody (AA 331-445)

Catalog No. ABIN781938

The Mouse Monoclonal anti-NEK2 antibody (Clone 2F6) (ABIN781938) specifically detects NEK2 in WB, IP, IHC (p) and EIA. The antibody is reactive with Human samples.

Quick Overview for NEK2 antibody (AA 331-445) (ABIN781938)

Target: NEK2 (NIMA (Never in Mitosis Gene A)-Related Kinase 2 (NEK2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NEK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 2F6

Product Details anti-NEK2 Antibody

Binding Specificity: AA 331-445

Specificity: This antibody recognizes NEK2.

Purification: Affinity Chromatography on Protein A

Immunogen: NEK2 antibody was raised against NEK2 (AAH43502, 331 a.a. ~ 445 a.a) partial recombinant protein with GST tag.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for NEK2

Target: NEK2 (NIMA (Never in Mitosis Gene A)-Related Kinase 2 (NEK2))

Alternative Name: NEK2

Background: NEK2, also called serine/threonine-protein kinase Nek2NimA-related protein kinase 2, NimA-like protein kinase 1 and HSPK 21, is a protein kinase involved in mitotic regulation that may have a role at the G2-M transition and may also play a role in meiosis. NEK2 has a nuclear localization and accumulates throughout S phase and shows maximal levels in late G2. This expression pattern is highly reminiscent of that of A and B cyclins.Synonyms: HSPK 21, NLK1, NimA-related protein kinase 2, Serine/threonine-protein kinase Nek2

Gene ID: 4751

NCBI Accession: NP_001191111

UniProt: P51955

Pathways: M Phase