CD247 antibody (AA 1-165)

Catalog No. ABIN782349

The Mouse Monoclonal anti-CD247 antibody (Clone 4A12-F6) (ABIN782349) specifically detects CD247 in WB, IP, IHC (p) and EIA. The antibody is reactive with Human samples.

Quick Overview for CD247 antibody (AA 1-165) (ABIN782349)

Target: CD247 (CD247 Molecule (CD247))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD247 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 4A12-F6

Product Details anti-CD247 Antibody

Binding Specificity: AA 1-165

Specificity: Recognizes CD247 / CD3Z.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Protein A Chromatography

Immunogen: CD247 antibody was raised against CD3Z (AAH25703, 1 a.a. ~ 165 a.a) full length recombinant protein with GST tag.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS, pH 7.2

Handling Advice: Avoid freeze-thaw cycles.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C or -80 °C.

Target Details for CD247

Target: CD247 (CD247 Molecule (CD247))

Alternative Name: CD247 / CD3Z

Background: CD3 consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta). The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). It is involved in signal transduction to the T cell interior following antigen recognition, which culminates in cytokine release, cellular proliferation. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.Synonyms: CD3 zeta chain, T-cell receptor T3 zeta chain, T-cell surface glycoprotein CD3 zeta chain, T3Z, TCRZ

Gene ID: 919

NCBI Accession: NP_000725

UniProt: P20963

Pathways: TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway