BCL11A antibody (AA 1-89)

Catalog No. ABIN782364

This anti-BCL11A antibody is a Mouse Monoclonal antibody detecting BCL11A in WB, IHC (p) and EIA. Suitable for Human.

Quick Overview for BCL11A antibody (AA 1-89) (ABIN782364)

Target: BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BCL11A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 3D9

Product Details anti-BCL11A Antibody

Binding Specificity: AA 1-89

Specificity: Recognizes Bcl-11A

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Protein A Chromatography

Immunogen: BCL11A (NP_060484, 1 a.a. ~ 89 a.a) partial recombinant protein with GST tag.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid freeze-thaw cycles.

Target Details for BCL11A

Target: BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))

Alternative Name: Bcl-11A

Background: This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.Synonyms: B-cell CLL/lymphoma 11A, B-cell lymphoma/leukemia 11A, BCL11A, COUP-TF-interacting protein 1, CTIP1, EVI9, Ecotropic viral integration site 9 protein homolog, KIAA1809

Gene ID: 53335

NCBI Accession: NP_060484

UniProt: Q9H165

Pathways: Regulation of Cell Size