TFF3 antibody (C-Term)

Catalog No. ABIN783349

This Rabbit Polyclonal antibody specifically detects TFF3 in WB and EIA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TFF3 antibody (C-Term) (ABIN783349)

Target: TFF3 (Trefoil Factor 3 (Intestinal) (TFF3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFF3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-TFF3 Antibody

Binding Specificity: C-Term

Specificity: This antibody detects TFF3 at C-term. TFF3 antibody is predicted to not cross-react with other TFF family members.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the carboxy terminus of human TFF3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for TFF3

Target: TFF3 (Trefoil Factor 3 (Intestinal) (TFF3))

Alternative Name: Trefoil Factor 3 / TFF3

Background: Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. Trefoil peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain and clustered in human chromosome 21q22.3. Trefoil Factor 3 (TFF3) is one of three trefoil peptides secreted by epithelial cells that line mucus membranes in the large and small intestines and lower respiratory tract. TFF3 is mainly active as a disulfide-linked homodimer and may have a role in promoting cell migration in healing processes. It is involved in the maintenance and repair of the intestinal mucosa.Synonyms: ITF, Intestinal trefoil factor, Polypeptide P1.B, TFI, hITF, hP1.B

Gene ID: 7033

NCBI Accession: NP_003217

UniProt: Q07654