ZBTB7A antibody (N-Term)

Catalog No. ABIN783361

This Rabbit Polyclonal antibody specifically detects ZBTB7A in WB, IHC (p), IF and EIA. It exhibits reactivity toward Human and Mouse.

Quick Overview for ZBTB7A antibody (N-Term) (ABIN783361)

Target: ZBTB7A (Zinc Finger and BTB Domain Containing 7A (ZBTB7A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZBTB7A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-ZBTB7A Antibody

Binding Specificity: N-Term

Specificity: This antibody detects ZBTB7A at N-term. At least two isoforms of ZBTB7A are known to exist, this antibody will recognize both isoforms. This antibody is predicted not to cross-react with other ZBTB protein family members.

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse.

Purification: Affinity Chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the amino terminus of Human ZBTB7A

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, 0.02 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ZBTB7A

Target: ZBTB7A (Zinc Finger and BTB Domain Containing 7A (ZBTB7A))

Alternative Name: ZBTB7A / Pokemon

Background: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB7A, also known as LRF, was initially identified as a potential target of the LAZ-3/BCL-6 oncogene. Later reports demonstrated that it could bind to the wild-type IST (inducer of short transcripts) elements of HIV-1 long terminal repeats (LTRs) and stimulate Tat activity on the HIV-1 LTR. More recently it ZBTB7A has been recognized as a proto-oncogene whose overexpression contributes to malignancy in breast cancer and functions as a co-repressor of the androgen receptor in prostate cancer cells.Synonyms: FBI-1, FBI1, Factor binding IST protein 1, LRF, Leukemia/lymphoma-related factor, POK (POZ and Krueppel) erythroid myeloid ontogenic factor, TIP21, TTF-I-interacting peptide 21, ZBTB7, Zinc finger and BTB domain-containing protein 7A

Gene ID: 51341

NCBI Accession: NP_056982

UniProt: O95365