SLAMF1 antibody (N-Term)

Catalog No. ABIN783432

This anti-SLAMF1 antibody is a Rabbit Polyclonal antibody detecting SLAMF1 in WB and EIA. Suitable for Human, Mouse and Rat.

Quick Overview for SLAMF1 antibody (N-Term) (ABIN783432)

Target: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLAMF1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-SLAMF1 Antibody

Binding Specificity: N-Term

Specificity: This antibody detects CD150 / SLAMF1 at N-term. Two isoforms of SLAMF1 are known to exist, this antibody will recognize both isoforms. SLAMF1 antibody is predicted to not cross-react with other SLAM protein family members.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the amino terminus of human SLAMF1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for SLAMF1

Target: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Alternative Name: CD150 / SLAMF1

Background: The signaling lymphocyte-activation molecule family member 1 (SLAMF1) is a novel receptor on T cells that potentiates T cell expansion in a CD28-independent manner. SLAMF1 is predominantly expressed by hematopoietic tissues. Reports suggest that the extracellular domain of SLAMF1 is the receptor for the measles virus and acts as a co-activator on both T and B cells. It is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations of the SLAM associated gene may be associated with X-linked lympho-proliferative disease (XLP).Synonyms: CDw150, Ipo-3, Signaling lymphocytic activation molecule, Slam

Gene ID: 6504

NCBI Accession: NP_003028

UniProt: Q13291