TYW3 antibody (Center)

Catalog No. ABIN783490

This Rabbit Polyclonal antibody specifically detects TYW3 in WB and EIA. It exhibits reactivity toward Human and Mouse.

Quick Overview for TYW3 antibody (Center) (ABIN783490)

Target: TYW3 (tRNA-YW Synthesizing Protein 3 Homolog (TYW3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TYW3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-TYW3 Antibody

Binding Specificity: Center

Specificity: This antibody detects TYW3 at Center. TYW3 antibody is predicted to not cross-react with other TYW protein family members. At least two isoforms of TYW3 are known to exist, this antibody will detect both isoforms.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the center of human TYW3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for TYW3

Target: TYW3 (tRNA-YW Synthesizing Protein 3 Homolog (TYW3))

Alternative Name: TYW3

Background: TYW3 is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation.Synonyms: C1orf171, tRNA wybutosine-synthesizing protein 3 homolog, tRNA-yW-synthesizing protein 3

Gene ID: 127253

NCBI Accession: NP_612476

UniProt: Q6IPR3