AP3B2 antibody (N-Term)

Catalog No. ABIN783508

This Rabbit Polyclonal antibody specifically detects AP3B2 in WB, IF, IHC (p) and EIA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for AP3B2 antibody (N-Term) (ABIN783508)

Target: AP3B2 (Adaptor-Related Protein Complex 3, beta 2 Subunit (AP3B2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AP3B2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-AP3B2 Antibody

Binding Specificity: N-Term

Specificity: This antibody detects AP3 complex subunit beta-2 (N-term).

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: Raised against an 18 amino acid peptide near the amino terminus of human AP3B2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for AP3B2

Target: AP3B2 (Adaptor-Related Protein Complex 3, beta 2 Subunit (AP3B2))

Alternative Name: AP3 Complex Subunit beta-2

Background: The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Unlike the homologous AP3B1, AP3B2-containing AP3 complexes are preferentially targeted to neuronal processes, and mice deficient in AP3B2 displayed compromised synaptic zinc stores.Synonyms: AP-3 complex beta-2 subunit, AP3B2, Adapter-related protein complex 3 subunit beta-2, Adaptor protein complex AP-3 beta-2 subunit, Beta 3B Adaptin, Clathrin assembly protein complex 3 beta-2 large chain, Neuron-specific vesicle coat protein beta-NAP, beta-NAP

Gene ID: 8120

NCBI Accession: NP_004635

UniProt: Q13367